Monday, December 31, 2012

On Freedom Fertility

I just wanted to take some time to write about obtaining my fertility medications through my prescription's preferred pharmacy, Freedom Fertility.

Thankfully for us, DH's health insurance is amazing and most everything is covered, infertility-wise. The biggest hoop I had to jump through so far was figuring out the pharmacy services.

At my first RE's office, they had a mail-order pharmacy that they preferred to use. It took alot of research and phone calls, but I finally found out I needed to use Freedom. Then, at the new RE's office, they have an actual fertility pharmacy located in the same plaza as them. Another pain in the butt, but I have to use Freedom.

Overall, Freedom is awesome. The RE faxes in the prescription and then Freedom will call you to gather information like your shipping address, insurance information (if it's your first time using them), and a credit card for the co-pay. You just tell them when you need it and it's done. They even email you when the item has shipped. Everything comes via Fed-Ex next day delivery, you just need to have someone home to sign for the package. Every person I've come in contact with at Freedom is super nice and helpful.

Plus, for me, the costs are great. For example, this past cycle I forgot to order my HCG trigger through Freedom, so I had to get one through that pharmacy by the new RE's office. I paid $89 for an HCG shot that I normally pay $5 for with my insurance through Freedom. Thank god for good insurance. In general, all of my prescriptions through Freedom have cost around $5 each. They give me syringes for free and they even give me my own sharp shuttle box, lol.

Friday, December 28, 2012

On Cycle #12 & IUI #4

I had my 4th IUI today - maybe fourth times the charm?

I had to drive to a further office because, due to the fire at my RE's office, they aren't doing procedures there. I definitely needed the "avoid ghetto" button on the GPS today, good lord.

Anyways, I got there and had my ultrasound. It showed the bigger follicle definitely released, but they were unsure if the smaller follicle released, although they think it did. My lining was only 5mm IE. The IUI nurse said that the lining measurement today isn't as important as what it looks like in 3 days. She said that they'll start me on the Endometrin tomorrow and the progesterone injections tomorrow. I go back in a week for bloodwork and ultrasound to see how the lining is doing. At this point, I really have no clue what else we could possibly do to boost up this lining, ya know? I have faith the progesterone injections will do the trick.

I turned my normal Negative Nancy thoughts into positive thoughts today. I refuse to let my lining number affect my thinking. We had 1, possibly 2, good eggs in there, great timing, and 30 million or so strong swimmers to work with. The progesterone injections are going to help my lining, the Lupron is going to help implantation and this is going to be my cycle. While I laid  there for the 20 minutes, I just kept thinking "those little guys are going to find my egg and it's going to be great." That's how I'm thinking today. :)

Edited to add: That was the most uncomfortable IUI I've ever had. I was feeling super crampy all morning, and what normally feels like a Pap felt very uncomfortable, almost painful. The IUI nurse said that sometimes when you release a large follicle, or multiple follicles, the fluid stays in your abdominal cavity and that's the pain/cramping you feel. Here's to hoping that different means good things.

Thursday, December 27, 2012

On Cycle #12: IUI Tomorrow!

I went yesterday for my CD12 bloodwork and ultrasound. Ultrasound showed my lining at 5mm (boo!) but the grade was IE/TL - and I think TL is the optimal grade for when you are doing IUI. Also, my follicles grew to 19mm and 14.3mm. I had to do 1 last Menopur shot in the afternoon, and then I triggered last night at 7pm. The awesome part is that we were at a bar, so I brought my trigger shot with me, and my friend injected me in the bathroom of the bar, lol.

Overall, besides some bloating and cramping - no side effects with the Menopur. One thing I noted is that between ultrasounds, my follicles didn't grow as much as I thought they would. I definitely thought I'd see more of a "boost", but besides adding an additional follicle to the mix (which I'm hoping grows a bit more so it releases tomorrow, as well), it seems to have kind of stunted the growth of the original follicle. Plus, I'm not seeing the huge improvement in my lining that I'd hope I'd see.

Something I've learned, as sort of a defense mechanism I guess, is not to get my hopes up. I go into each ultrasound not having high hopes for my lining. I go into each IUI not really thinking it will work. Of course, there is always that devastation when it doesn't work - but it has helped my mental health a bit. I remember how sad I was when that first Clomid/IUI cycle didn't work. I was utterly devastated - I thought for sure it would be IT. And since then, each failing cycle has almost hurt a little less. I hate the idea of having lost hope, but I think I'm kind of at that point. I go through all of the motions and I'll do whatever the doctor and nurses say, but I never really think we'll be successful.

Monday, December 24, 2012

On Cycle #12: CD8 & CD10 Ultrasounds & Starting Menopur

I had my CD8 ultrasound and bloodwork on Saturday. It showed 4mm lining (boo!) and a 14.3mm follicle on my right ovary. They had me start Menopur 75iu that night. DH prepped the shot and administered it for me. It actually was kind of painful when he pushed the meds (the needle itself didn't hurt) but other than that, absolutely no side effects.

I went for my follow up ultrasound and bloodwork today - lining was 5mm, which is still sucky but an improvement for me and my follicle grew to 16mm and I have another one sneaking up at 13mm. Twins?! LOL. I am doing 2 more days of Menopur, then go back for ultrasound on Wednesday. I am willing to bet I'll trigger Wednesday night and IUI Friday.

Merry Christmas to all!!!

Friday, December 21, 2012

On Weighing In & the Sickies

I almost forgot to do my weekly scale hop this morning, but was pleasantly surprised with a 1.6lb loss. :)

I only hit the gym once this week, due to a crazy schedule and an illness. I've had a sore throat, chest congestion with cough, ear pain, and sinus pressure since Monday. I went to my regular endocrinologist on Wednesday for my quarterly check-up and he listened to my lung sounds and immediately prescribed me a Z-pack. I've felt absolutely awful since then - my daily breakfast is my Z-pack, Delsym, DayQuil, tea with lemon and honey, and a large Wawa Chicken Noodle soup. Yesterday, DH brought me home lidocaine throat stuff, so I've been using that as well.

DH thinks I have the flu. I got a flu shot this year (like every year) but he thinks that the extra progesterone suppressed my immune system and that's why I'm so bad right now. I had a much less intense illness similar to this about 3 weeks ago, so he thinks I never fully got over that and now, here I am. I also have an itchy rash on my hip/butt cheek where he was doing the progesterone injections, so I am probably dying and falling apart, lol. He says if I'm not better by Sunday, I'm paying his urgent care a visit. LOL.

Tomorrow I go for my ultrasound and bloodwork and should know my injectible protocol by tomorrow night. :)

Tuesday, December 18, 2012

On Uterine Lining

Since my primary issue seems to stem from my uterine lining, I decided to do a little internet research on it.

From looking at my ultrasound slips, I've noted there are 3 types of lining "grades" that my RE likes to know about: TL, IE, and HH.

From Livestrong: "The pattern changes during the menstrual cycle; a good pattern in the first half of the cycle, before ovulation, is not a good pattern after ovulation. A trilaminar lining, also called a triple lining or a TL pattern before ovulation is best for conception. Once your body produces progesterone, your lining should change to a homogenous pattern, sometimes called an HH pattern. A lining of between 7 and 12 millimeters is optimal for conception, but people can and do get pregnant with linings as thin as 3 millimeters, Dr. Timothy Hickman of Houston IVF reports on the Fertility Today website..."

From INCIID: "As you approach your LH surge, it should be above 6 mm, ideally between 8 and 12 mm. (If it is much more than that, it may be advisable to ask about a hysteroscopy or sonohysterogram to see if perhaps there is a polyp inside the uterus). You want to have a triple stripe pattern around the time of the LH surge and ovulation. Towards the time of implantation, you want to have a more integrated HH or IE pattern. The triple stripe occurs in response to estradiol; the HH/IE conversion is in response to progesterone. It should also be noted that, although most doctors prefer the above pattern of linings, there is no conclusive research on whether a better pattern actually results in higher pregnancy rates..."

Then, I found this article about pregnancy rates and lining, which shows that the lining should be at HH 3 days after transfer (in IVF, so you'd have to conclude the same should be true for IUI).

I had an IE pattern yesterday at my baseline, now time to see how it goes the rest of the cycle. At my last cycle, I had HH (I forget what thickness) at 7DPIUI, and that's when the nurse said I needed the progesterone injections daily versus every other day.

On Cycle #12: Baselines

I went to the RE's office yesterday for my CD3 bloodwork and ultrasound. AF came with a venegence on Saturday, first with an awful headache that I originally attributed to being hungover, and then with cramps. I feel as though AF is becoming more and more intense each cycle. It took 5 days for her to come after stopping both the Endometrin and the progesterone injections. I'm hoping that means the progesterone injections were doing their job and bulking my lining up a bit.

The nurse called last night and said everything looks good so far. When I took a peek at my ultrasound slip, it showed my lining at 3mm with a grade of IE. I need to do some more research into the different "grades" of lining. Anyways, we talked about the injectibles. She said that since I make mature follicles on my own, they won't give me the injectibles to stimulate my ovaries, but rather just to help in the lining department. To be honest, I was kind of disappointed because I was looking forward to the chance of multiples, but it is what it is. I go back on Saturday for another ultrasound and bloodwork, and then that night I will probably start the Menopur.

Friday, December 14, 2012

On Everyone Else

Today it feels like one of those days where everyone else is pregnant except for me.

I swear, in all of my Fertility Friend 'groups', all sorts of women, many who haven't been trying as long as me, are getting pregnant and getting stheir BFPs. And I hate having the attitude of "I deserve it more" but today is definitely one of those days.

I'm sure alot of it is hormones (still waiting for friggin AF to get here) and frustration at the thought of moving onto Cycle 12, but lord... when will it be my turn?

Thursday, December 13, 2012

On TTC Readings

For the past few months, I've always felt like December was my month. I, for whatever reason, thought that I'd be announcing my pregnancy to my family on Christmas. I always had it in the back of my mind, each cycle, "that's ok, it's not December yet". I couldn't quite remember why I always thought December was "it", but scrolling through some old emails, I remembered.

I paid for 2 different TTC readings. I know alot of people don't believe in this stuff, but I'm a partial believer. I don't guide my entire life by these things, but I like getting readings for some insight into things.

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The first one was through TTC Baby Love Predictions. I think I paid $15 for a reading about all children. I sent my first name, my husband's first name, and that we'd never had a child and no pregnancy losses. I think I also sent a picture. Here's what she responded with:

When I spoke with your baby to come he said hes a precious boy. That you will FIND OUT WITH A POSITIVE TEST DEC OF 2012 OR CONCEIVE DEC OF 2012 OR GIVE BIRTH/EXPECTED DUE DATE OF DEC OF 2013. When I spoke with your next baby to come she said that shes a precious girl. That you will FIND OUT WITH A POSITIVE TEST NOV OF 2016 OR CONCEIVE NOV OF 2016 OR GIVE BIRTH/EXPECTED DUE DATE OF NOV OF 2017.  

The second one was through Psychic Sky. I think I paid $10 for a reading about first child. I sent my first name, my husband's first name, and that we'd never had a child and no pregnancy losses. I think I also sent a picture. Here's what she responded with:

As I focus in and make a connection with you and the spirit of your unborn child. I get a strong sense that the month of November will be very significant with pregnancy for you. This could be referring to conception or a positive test in November of 2012 or giving birth in November of 2013. I feel a boy's presence as I focus on this pregnancy.

To simplify things I see November as conception, find out, or birth month, and I see the baby being a boy. 


 

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Overall, I felt like the readings provided me with some peace - like hey, this is gonna happen. When I first got the readings (I think in the spring?), November/December seemed SO far away. Well, November is gone and we are halfway through December, and still no pregnancy. So, part of me is like, ok, maybe I'll get pregnant in the early Spring and end up with a November or December baby, like they said.

Another site I like is Free Tarot Readings. I like going there before something big is going to happen with the RE (like IUI) to get some vision on things. (I swear, I'm not a nut.)

I just did a reading, and this is what I got:

Card 1 (The World) : How you feel about yourself now  »
You are about to reach, or are already enjoying, a period of total fulfilment, wholeness and satisfaction - the arrival of your hearts desires. You feel satisfied with what you have achieved and are enjoying the rewards of past efforts. A time of happy outcomes, material wealth and greater spiritual awareness.

Card 2 (The High Priestess) : What you most want at this moment  »
The cards suggest that what you most want at this time is for a secret to be revealed, a secret held deep within yourself or another? Go within and listen to your heart and instincts. The appearance of The High Priestess tells you that the power of the divine feminine is with you, trust it.

Card 3 (The Chariot) : Your fears  »
The word failure isn't in your vocabulary. You are worried things are more of a struggle than you expected, with more delays and frustrations. Things aren't going to plan at all, just chill out, calm that mind of yours and you'll find the strength to battle on until you succeed. This is a period of movement and change and conflicts ending in victory.

Card 4 (The Emperor) : What is going for you  »
You are self-assured and more than capable of influencing people or events to achieve what you want. What's more, support and guidance from your father, husband/partner or a man of significance in your life is there for the asking. Go for it!

Card 5 (The Sun) : What is going against you  »
You may experience a few delays on your quest for success and achievement but don't worry, you'll get there in a blaze of glory. Success may go to your head a little so a little modesty wouldn't go amiss. Other than a few minor delays, look forward to a period of joy and happiness. If you are experiencing problems with conceiving a baby, The Sun often heralds good news around children and a much wanted pregnancy or birth of a longed-for baby.

Card 6 (Death) : Outcome  »
This is a transformational time for you. However turbulent or perhaps distressing some of the events in your life may be, endings always leave room for brand new beginnings. This is a fresh start in life for you, embrace it and live every day as though it was your last, life is for living!

Wednesday, December 12, 2012

On Cycle #11: BFN

With no surprise to me whatsoever, the RE's office called late yesterday afternoon and left a message that my beta was negative. I'm glad I didn't interrupt my afternoon nap by answering the phone and instead just listened to the voicemail my favorite nurse left me.

I saw her when I went in for my bloodwork, and she said she had her fingers crossed. I told her I was sure it was going to be negative, since I had tested, and she said "you know you aren't supposed to do that!" Do they really think we aren't going to test on our own? LOL.

I tested on 11DPIUI and 14DPIUI and both were stark white. The stark whiteness doesn't even shock me anymore. I wait a minute or two and then toss the damn things in the trash. What's the point?

This is the first cycle EVER where I haven't cried about the BFN. I think I just had so little hope going into it, thanks to my shitty lining, that I didn't even think it was possible. Of course, typing this out, I feel a little sad and like I could cry, but it's not even worth the tears. The tears don't change anything, me doing everything the doctor says doesn't change anything, nothing is in our control, obviously. I feel like I'm slowly resigning myself to the fact this may not happen for us. I know I'm not at the end of the line with treatments and options, but if it hasn't happened with all these other things, why would it suddenly happen? At this point, I'd welcome a chemical pregnancy, just for the knowledge that it IS possible. At this point, I'm being lead, almost blindly, into things that may never prove fruitful.

Anyways, I had written on my callback form that I wanted to start injectibles this next cycle, and she said for me to come in for my CD2 or CD3 ultrasound and bloodwork and then they'd figure out what medication I would use. She said since I already have the Menopur, maybe I'll use that.

I haven't tracked a single thing in weeks, mostly due to laziness and having been on vacation the past few days (which was fabulous, by the way)... so I'm making myself start up again. If I'm not going to dedicate to Weight Watchers and the gym, I need to stop paying for them because it's just such a waste.

On My TTC Journey, Thus Far

This is a post I'm hoping to update as I go along on this journey with all of my "stats"...

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Off BCP & Temping since 02/12

Using OPKs, D3, & B6 since 04/12

Luteal Phase Defect & Thin Endometrial Lining

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06/18/12 - Consultation with First RE's office
06/19/12 - HSG = Normal
07/02/12 - 7DPO Bloodwork = Slightly low progesterone
07/07/12 - Baseline Bloodwork = All Normal
07/10/12 - Baseline Ultrasound = All Normal
07/23/12 - Follow-up appointment with First RE's office, recommended to do Clomid with IUI/trigger

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Cycle #7 08/02/12 - 1st Medicated Cycle - Clomid 50mg + Ovidrel + IUI + Progesterone = BFN
08/13/12 CD12 U/S = 4mm lining, 23mm follice on right, 14mm & 15mm follicle on left, triggered at 9:30pm
08/15/12 = IUI at 9:30am

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Cycle #8 - Tamoxifen 20mg + Ovidrel + IUI + Progesterone = BFN
09/10/12 CD12 U/S = 4mm lining, 20mm follice on right - was surging on my own, so triggered at 2pm
09/11/12 = IUI at 9:30am

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09/26/12 - "Next Steps" appointment with First RE's office - Suggested by RE to move to injectibles after Cycle #9. Seeking 2nd opinion on 10/18/12.

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Cycle #9 - Break Cycle. No temping, no meds, no OPKs.

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10/10/12 - Accupuncture

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10/18/12 - New RE suggests monitoring cycle and possible use of Menopur. Sees no evidence I don't produce "good eggs" on my own.

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Cycle #10 = Natural monitoring cycle by new RE with progesterone after O = BFN
10/25/12 CD11 U/S = 3.5mm lining, 17mm follicle.
10/27/12 CD13 U/S = 5mm lining, 20mm follicle. Surging on my own - earliest ever without medications!

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Cycle #11 = Natural IUI cycle with trigger & progesterone after O = BFN
11/24/12 CD11 U/S = 6mm lining (thickest EVER!), 19.6mm follicle. Triggered with 10000 units HCG at 7:15pm.
11/26/12 = IUI = U/S showed egg release, lining at 4mm. 41 million post wash.
12/03/12 = 7DPIUI b/w & u/s = lining at 5mm
12/04/12 = started progesterone injections

Recommendation for next cycle is injectibles

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Cycle #12 - Menopur 75iu CD8 - CD12 + HCG Trigger + IUI = BFP
12/17/12 CD3 U/S = 3mm IE, looking good for injectibles for lining
12/22/12 = CD8 U/S = 4mm IE lining, 14.3mm follicle on right ovary, started Menopur 75iu that night.
12/24/12 = CD10 U/S = 4mm IE lining, 16mm & 13mm follicles on right ovary
12/26/12 = CD12 U/S = 5mm IE/TL lining, 19mm & 14.3mm follicles on right. Last Menopur 75iu at 4:15pm, triggered with 10000 units HCG at 7pm.
12/28/12 = IUI = U/S showed egg release of larger follicle/possible release of smaller follicle, lining at 5mm IE. 30 million post wash.
12/29/12 = started Endometrin 100mg 3x daily & Progesterone injections
01/04/13 = 7DPIUI b/w & u/s = lining at 4mm. Did Lupron shot.
01/07/13 = 8pm = BFP on Wondfo internet cheapie! 9:30pm = BFP on digital!
01/08/13 = told DH
01/10/13 = 13DPO = Beta 306, Prog. 62
01/14/13 = 17DPO/4wk3d = Beta 1816
01/17/13 = 20DPO/4w6d = Beta 6007, saw little bean on ultrasound!
01/29/13 = 6w4d = TWINS! Baby A = 128bpm, Baby B = 120bpm
02/11/13 = 8w3d = Baby A =167, Baby B = 163
02/22/13 = 10w = Baby A = 163, Baby B = 164

Wednesday, December 5, 2012

Tuesday, December 4, 2012

On Being Hopeful & Thankful

After my complete breakdown last night, and my puffy eyes this morning, I felt absolutely desperate about my situation.

I was scheduled to see my favorite nurse at the RE's office to get a progesterone injection at 8:15am. When I went there, I saw the damage that had been done to their building as a result of the fire. They are now working in another, older, building that hadn't really been used in years. They have no phone lines, so they are all using their private cell phones to contact patients. They don't have fax machines, so they are using the fax machine at the pharmacy across the street. The absolute dedication of this staff is amazing to me. My nurse relayed to me that they were able to save all of the embryos from the fire - it truly touched my heart.

My nurse told me that not only is my endometrial lining thin, but it also isn't the best 'grade' to sustain pregnancy. They like it to "switch over" to a certain grade after ovulation and mine doesn't do that, so they are hoping the progesterone injections help with that. I'll do the injections every day after O, in addition to the 300mg Endometrin. I'm going to be a progesterone monster, lol.

After receiving my injection, and progesterone supplies for our vacation, I spoke to my nurse about moving to injectibles. The conversation with her made all the difference in the world. She has a very "kick ass" attitude, and talks to me like I'm her friend. She told me she really studied my chart before asking the RE the best steps, and it made me feel like they are really trying to fix the underlying problem and treating me as an individual patient, not a number. She said if I wasn't pregnant next cycle, I should definitely move to the injectibles. I told her that if I'm not pregnant this cycle (I honestly am not hopeful about it at all), I want to move to them for next cycle.

She is going to have them handle calling my pharmacy to get them all ready for me. I don't know my exact protocol yet, but she said because I already ovulate on my own, and early, I'll probably only need 5 days of low dose injections. She said I'll still do an HCG trigger, IUI, Lupron, and my progesterone. She said the biggest risk with the injections is overstimulation and multiples. Honestly, after this struggle, I would welcome multiples. I don't want to be Octomom, but twins would be more than welcome. Also, because they monitor you so closely, we'd know ahead of time if this is an issue and she said I could cancel the cycle or do emergency IVF. Overall, her attitude was very much "you've got this" and she told me it would be easier, side effect wise, for me versus the oral medications.

Because I've been such a whiny bitch, I want to come up with a short list of things I'm thankful for in this journey.
  • A supportive husband who deals with my crazy ass, and comforts me during my crazy and has never, not once, complained about a single thing ever. "Look, in my opinion, the best thing you can do is find a person who loves you for exactly what you are. Good mood, bad mood, ugly, pretty, handsome, what have you, the right person is still going to think the sun shines out your ass. That's the kind of person that's worth sticking with." - that's my husband
  • My husband's awesome insurance that covers all of this stuff with very little OOP cost to us.
  • Living in an area where we have a few excellent RE practices to choose from.
  • Being able to seek treatment before the "1 year of trying" guideline.
  • Having the ability to seek a 2nd opinion about this journey, and falling in love with a new RE practice.
  • The support that my friends and family who know about our issues have shown me. They, too, deal with my crazy and haven't complained about it, yet.
  • Having friends who are also going through the same thing that TRULY understand the emotions associated with it. I don't wish this on anyone, but having friends on the same journey makes a huge difference.
  • Thong pantyliners - life on Endometrin would not be the same without them, lol.

Monday, December 3, 2012

On Cycle #11: 7DPIUI Ultrasound & Bloodwork and Next Steps

I had my 7DPIUI bloodwork and ultrasound today. I didn't get my hopes up about my lining, and I'm glad I didn't - it was only 5mm. This is after the increased Endometrin (300mg daily) and alot of hoping and praying on my part.

The nurse, actually, my favorite nurse, just called me a little bit ago with the results and with some news. The office caught on fire today. She said it was really bad and that they are all working off of their cell phones in another building. I felt awful but it speaks to the practice's dedication to their patients.

Anyways, she told me about my lining and asked if I'd been doing my Endometrin as prescribed. I, admittedly, had slacked off in previous cycles, missing doses and what not - but had really been on my game this cycle. I friggin plan my life around this crap and the ridiculous side effects. She said that I need to come in tomorrow to learn how to give myself progesterone shots. Something else to add to my repertoire.

She told me not to lose hope about this cycle (is not losing hope even possible when you are on this journey and the doctor's office calls with any news other than "you're pregnant!"?), but that the RE's recommendation is that if I'm "not pregnant in a few cycles", I should move to injectibles.

The same news the original RE told me.

The reason I sought a 2nd opinion from this practice.

The thing is, moving to injectibles in and of itself is not all that distressing to me. I know it'll be a lifestyle change, and there will be alot of work on my part (not that there isn't already), but I'm accepting of that. I have already accepted that my husband and I will not get pregnant "the easy way". Any baby I have will be the result of endless talks with nurses and doctors, endless needle pokes, endless ultrasounds, and endless tears. We will not ever get to be carefree about this journey. Every little thing will have some meaning to us along the way.

The thing that frightens me about the injectible medications is that if they don't work, it's onto IVF we go.

Of course, DH had already left for work when I got the phone call. So, when I called him with the update, I really tried to stay strong. He asked if injectibles are what I want to do - but the answer is always the same, what choice do I have? I want a child. I'll do whatever I need to do to have a child. THAT is what it comes down to.

I hung up the phone with him and have been just crying since.

I just made this my Facebook status, and it basically completely sums up how I feel - my complete & total Type-A personality does not understand a task where you do all of your research, follow all of the directions, do everything right, and still fail. I am not accustomed to not achieving things I set my mind to and do my best at.